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Data were pooled from three different clinical trials, each similar in design and inclusion/exclusion criteria, primary endpoints and assessment schedules. To determine if escitalopram is more effective than citalopram in patients with severe depression.

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Ighly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Data sources include IBM Watson Micromedex updated 10 Aug 2020 Cerner Multum updated 3 Aug 2020 Wolters Kluwer updated 10 Aug 2020 andothers.

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