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The question now relates to the mechanisms associated with this evocation process, i. how does the activity of BMP control the dynamics of these anterior neural GRNs? Furthermore, if induction is actually an evocation Waddington, 1954 this would imply that transplantation of the dorsal lip to speman tablets review prospective posterior/ventral side in the Spemann and Mangold experiment should not be interpreted as the establishment of a new programme of gene expression in the host but rather as the unveiling speman tablets review a latent programme.

Altogether, these observations suggest a reformulation of neural induction, and thereby of the activity of Spemann's organizer, as the degree to which an intrinsic, and perhaps universal, genetic programme is evoked and the molecular mechanisms associated with this process.

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When this area was fate-mapped into later embryonic stages, he found that the gray crescent gave rise to the dorsal cells that initiate gastrulation. Spemann found that a certain piece of the two-cell stage newt embryo, termed the gray crescent for its color, was completely required for embryonic growth. ...

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